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How Mistakes in Meiosis Can Result in Down Syndrome or Death of an Embryo

In this minds-on analysis and discussion activity, students learn how a mistake in meiosis can result in Down syndrome. Students also analyze karyotypes to learn how other mistakes in meiosis can result in the death of an embryo. Finally, students consider how a health problem can be genetic, but not inherited.

The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity supports the Next Generation Science Standards (NGSS).

AttachmentSize
Meiosis Mistake SH.docx1.15 MB
Meiosis Mistake SH.pdf380.18 KB
meiosis mistakes TN.docx70.74 KB
meiosis mistakes TN.pdf117.79 KB
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iwaldron's picture

2020 revision

Submitted by iwaldron on Wed, 09/30/2020 - 8:47am.

Both the Student Handout and Teacher Notes have been entirely updated and revised to enhance student learning.

Ingrid

Serendip Visitor's picture

Alternative Title for this Unit

Submitted by Serendip Visitor (guest) on Thu, 06/02/2016 - 12:17pm.

Instead of: How "MISTAKES" in Cell Division Can Result in Down Syndrome and Miscarriages maybe we can say:

How VARIANCES and/or IRREGULARITIES in Cell Division Can Result in Down Syndrome and Miscarriages. We want to avoid spreading the notion that individuals with Down syndrome are "mistakes". Same goes for other individuals with congenital conditions. Also, this lesson presents a great opportunity to invite individuals with Down syndrome to the classroom to ultimately help our school communities become a more inclusive and companionate educational institutions. (Human Diversity and Genetic Variances)
My humble opinion....
Red

Patel's picture

Biology

Submitted by Patel (guest) on Tue, 03/22/2016 - 7:39pm.

thanks for the answers! really needed something to double check my answers!

Serendip Visitor's picture

answers

Submitted by Serendip Visitor (guest) on Mon, 04/27/2015 - 10:43am.

post answer key to the worksheet!!!
please

iwaldron's picture

Answers to Questions in Student Handout

Submitted by iwaldron on Tue, 04/28/2015 - 9:15am.

We do not have an answer key for Genetics Supplement. However, I believe that the information in the Student Handout and Teacher Notes should make it relatively easy to prepare a key. If you have any additional questions beyond the information in the Teacher Notes, please let me know (iwaldron@sas.upenn.edu) and I will be happy to answer your questions.

Serendip Visitor's picture

biology

Submitted by Serendip Visitor (guest) on Thu, 04/09/2015 - 5:54pm.

first time visitor - haven't done it yet

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Download Minds-On Activities for Teaching Biology

Introduction and Activities Listing

Intro and Biological Molecules

Cell

Cell Structure and Function

Cellular Respiration and Photosynthesis

Cell Division

Cell Division

Genealogy

Genetics

Genealogy

Molecular Biology

Natural Selection

Evolution

Natural Selection

Ecology

Runner

Human Physiology and Health

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Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. To preserve the value of these learning activities for other teachers, please do not post keys for any questions from any of these activities!

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Authors

Dr. Ingrid Waldron is Professor Emerita in the Biology Department at the University of Pennsylvania. Co-authors include Dr. Jennifer Doherty, who is an Assistant Professor in the Physiology Department at Michigan State University, and Dr. Lori Spindler, who is a Lecturer in the Biology Department at the University of Pennsylvania. They have developed these activities in collaboration with colleagues at Penn and middle school and high school teachers in the Philadelphia area. We are grateful to Craig Douglas for his generous help with graphics.

 

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